antibody

COL4A6, ID (COL4A6, Collagen alpha-6(IV) chain)

034095

200 ul

polyclonal

domestic rabbit

nonconjugated

COL4A6, ID (COL4A6, Collagen alpha-6(IV) chain)

rabbit

Pab

Antibodies

200 ul

IgG

This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene. Applications: Suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Western Blot: 1:100-1:500 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Hu

COL4A6, Collagen alpha-6(IV) chain

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa828-858 in the central region of human COL4A6, UniProt Accession #NP_001838.2; NP_378667.1; Q14031 Cellular Localization: secreted, extracellular space, extracellular matrix, basement membrane.

Recognizes human COL4A6.

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids aa828-858 in the central region of human COL4A6, UniProt Accession #NP_001838.2; NP_378667.1; Q14031 Cellular Localization: secreted, extracellular space, extracellular matrix, basement membrane. Specificity: Recognizes human COL4A6. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

WB

-20°C

1. Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press : 2. Bailey, S.D., et al. Diabetes Care (2010) In press : 3. Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) : 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) 5. Skovbjerg, H., et al. BMC Cancer 9, 136 (2009) :

https://usbio-images.r.worldssl.net/prodimages/1/034095_1.jpg