CEACAM7, ID (CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2)

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product summary

company name :

US Biological

product type :

antibody

product name :

CEACAM7, ID (CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2)

catalog :

033746

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

033746

Product wo Prefix :

CEACAM7, ID (CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

CEA-related cell adhesion molecule 7 (CEACAM7,CGM2) belongs to the carcinoembryonic antigen (CEA) family. It encodes a glycosyl phosphatidyl inositol (GPI)-linked glycoprotein which is only found on the apical surface of highly differentiated epithelial cells adult colon and on a small epithelial cell population in pancreatic ducts. CEACAM7 expression is completely lost upon malignant transformation already in hyperplastic polyps and early adenomas as well as in adenocarcinomas of the colon. Like all members of the CEACAM family, it consists of a single N domain, with structural homology to the immunoglobulin variable domains, followed by one immunoglobulin constantlike A domain. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CEACAM7, CGM2, Carcinoembryonic antigen-related cell adhesion molecule 7, Carcinoembryonic antigen CGM2

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 112-140 in the central region of human CEACAM7, UniProt Accession #Q14002; NP_008821.1.

Specificity :

Recognizes human CEACAM7.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 112-140 in the central region of human CEACAM7, UniProt Accession #Q14002; NP_008821.1. Specificity: Recognizes human CEACAM7. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Messick, C.A., et al. Surgery 147(5):713-719(2010). 2. Douard, R., et al. Surgery 139(4):556-562(2006). 3. Zhang, Z., et al. Protein Sci. 13(10):2819-2824(2004). 4. Grimwood, J., et al. Nature 428(6982):529-535(2004). 5. Scholzel, S., et al. Am. J. Pathol. 156(2):595-605(2000)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/7/033746_1.png