CDC45L, ID (CDC45, CDC45L, CDC45L2, Cell division control protein 45 homolog, PORC-PI-1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CDC45L, ID (CDC45, CDC45L, CDC45L2, Cell division control protein 45 homolog, PORC-PI-1)

catalog :

033603

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

033603

Product wo Prefix :

CDC45L, ID (CDC45, CDC45L, CDC45L2, Cell division control protein 45 homolog, PORC-PI-1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene was identified by its strong similarity with Saccharomyces cerevisiae Cdc45, an essential protein required to the initiation of DNA replication. Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18, the minichromosome maintenance proteins (MCMs) and DNA polymerase, which is important for early steps of DNA replication in eukaryotes. This protein has been shown to interact with MCM7 and DNA polymerase alpha. Studies of the similar gene in Xenopus suggested that this protein play a pivotal role in the loading of DNA polymerase alpha onto chromatin. Multiple polyadenlyation sites of this gene are reported. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CDC45, CDC45L, CDC45L2, Cell division control protein 45 homolog, PORC-PI-1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 236-263 in the central region of human CDC45L, UniProt Accession #O75419.

Specificity :

Recognizes human CDC45L.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 236-263 in the central region of human CDC45L, UniProt Accession #O75419. Specificity: Recognizes human CDC45L. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IHC WB

Storage Temperature :

-20°C

Reference :

1. Chowdhury, A., et al. Mol. Cell. Biol. 30(6):1495-1507(2010) 2. Im, J.S., et al. Proc. Natl. Acad. Sci. U.S.A. 106(37):15628-15632(2009) 3. Ballabeni, A., et al. J. Biol. Chem. 284(5):3028-3036(2009) 4. Enjuanes, A., et al. Cancer Res. 68(24):10178-10186(2008) 5. Hoskins, J.M., et al. Clin. Cancer Res. 14(6):1788-1796(2008)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/15/033603_1.png