CD8B1, CT (CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8b) (APC) | US Biological 033550-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD8B1, CT (CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8b) (APC)

catalog :

033550-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

033550-APC

Product wo Prefix :

CD8B1, CT (CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8b) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. Applications: Suitable for use in Western Blot, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain, CD8b

Immunogen :

CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human CD8B1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: CD8B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human CD8B1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Chen, M.L., et al. Eur. J. Immunol. 39(12):3423-3435(2009) Thakral, D., et al. J. Immunol. 180(11):7431-7442(2008) Stove, V., et al. J. Virol. 79(17):11422-11433(2005) Moody, A.M., et al. J. Biol. Chem. 278(9):7240-7246(2003)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/43/033550-APC_1.jpg