CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40)

catalog :

033512

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

033512

Product wo Prefix :

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD40

Immunogen :

CD40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human CD40.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: CD40 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 246-276 amino acids from the C-terminal region of human CD40. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Rodriguez-Rodriguez, L., et al. J. Rheumatol. 37(10):2076-2080(2010) Lewis, J.P., et al. Genomics 96(4):211-219(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Blanco-Kelly, F., et al. PLoS ONE 5 (7), E11520 (2010) : Soliman, M.A., et al. Egypt J Immunol 16(1):61-70(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/10/033512_1.jpg