CD160, ID (CD160, BY55, CD160 antigen, Natural killer cell receptor BY55, CD160)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD160, ID (CD160, BY55, CD160 antigen, Natural killer cell receptor BY55, CD160)

catalog :

033462

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

033462

Product wo Prefix :

CD160, ID (CD160, BY55, CD160 antigen, Natural killer cell receptor BY55, CD160)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

CD160 is an 27kD glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CD160, BY55, CD160 antigen, Natural killer cell receptor BY55, CD160

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 56-82 in the central terminal region of human CD160, UniProt Accession #O95971.

Specificity :

Recognizes human CD160.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 56-82 in the central terminal region of human CD160, UniProt Accession #O95971. Specificity: Recognizes human CD160. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Schmitt, C., et al. Genes Immun. 10(7):616-623(2009). 2. Kolz, M., et al. PLoS Genet. 5 (6), E1000504 (2009). 3. Giustiniani, J., et al. J. Immunol. 182(1):63-71(2009). 4. Cai, G., et al. Nat. Immunol. 9(2):176-185(2008)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/31/033462_1.pdf