This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
CD105, ID (E395) (ENG, END, Endoglin, CD105) (AP)
catalog :
033445-AP
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
AP
reactivity :
human
product information
Catalog Number :
033445-AP
Product wo Prefix :
CD105, ID (E395) (ENG, END, Endoglin, CD105) (AP)
Host :
rabbit
Product Type :
Pab
Conjugate :
AP
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
CD105 is a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds TGFB1 and TGFB3 with high affinity. Mutations in its gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia.
Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.
Recommended Dilution:
Immunohistochemistry: Formalin-fixed, paraffin-embedded sections
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu Mo
Alternate Name :
ENG, END, Endoglin, CD105
Immunogen :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 380-409 in the central region of human CD105, UniProt Accession #P17813.
Specificity :
Recognizes human CD105. Species crossreactivity: mouse
Purity :
Purified by Protein A/G affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Purity: Purified by Protein A/G affinity chromatography.
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 380-409 in the central region of human CD105, UniProt Accession #P17813.
Specificity: Recognizes human CD105. Species crossreactivity: mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
4°C Do Not Freeze
Reference :
Chen,Y., Ann. Neurol. 66 (1), 19-27 (2009) Rius,C., Blood 92 (12), 4677-4690 (1998)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/44/033445-AP_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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