This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
CCR8, CT (CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198)
catalog :
033433
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
033433
Product wo Prefix :
CCR8, CT (CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region.
Applications:
Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution:
Western Blot: 1:1000
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198
Immunogen :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 305-335 in the C-terminal region of human CCR8.
Specificity :
Recognizes human CCR8.
Purity :
Purified by Protein A and peptide affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A and peptide affinity chromatography.
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 305-335 in the C-terminal region of human CCR8.
Specificity: Recognizes human CCR8.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC WB
Storage Temperature :
-20°C
Reference :
Mutalithas, K., et al. Clin. Exp. Allergy 40(8):1175-1185(2010) Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/22/033433_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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