CCR8, CT (CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198) (AP) | US Biological 033433-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CCR8, CT (CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198) (AP)

catalog :

033433-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

033433-AP

Product wo Prefix :

CCR8, CT (CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

CCR8 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are important for the migration of various cell types into the inflammatory sites. This receptor protein preferentially expresses in the thymus. I-309, thymus activation-regulated cytokine (TARC) and macrophage inflammatory protein-1 beta (MIP-1 beta) have been identified as ligands of this receptor. Studies of this receptor and its ligands suggested its role in regulation of monocyte chemotaxis and thymic cell apoptosis. More specifically, this receptor may contribute to the proper positioning of activated T cells within the antigenic challenge sites and specialized areas of lymphoid tissues. CCR8 is located at the chemokine receptor gene cluster region. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

CCR8, CKRL1, CMKBR8, CMKBRL2, C-C chemokine receptor type 8, CC chemokine receptor CHEMR1, Chemokine receptor-like 1, GPR-CY6, TER1, CDw198

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 305-335 in the C-terminal region of human CCR8.

Specificity :

Recognizes human CCR8.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 305-335 in the C-terminal region of human CCR8. Specificity: Recognizes human CCR8. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Mutalithas, K., et al. Clin. Exp. Allergy 40(8):1175-1185(2010) Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Davila, S., et al. Genes Immun. 11(3):232-238(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 18(5):1651-1658(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/033433-AP_1.jpg