This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
CCR1, NT (CCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191)
catalog :
033428
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
033428
Product wo Prefix :
CCR1, NT (CCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
CCR1 encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
CCR1, CMKBR1, CMKR1, SCYAR1, C-C chemokine receptor type 1, HM145, LD78 receptor, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, CD191
Immunogen :
CCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2~31 amino acids from the N-terminal region of human CCR1.
Specificity :
Human
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A affinity chromatography.
Immunogen: CCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2~31 amino acids from the N-terminal region of human CCR1.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC IHC WB
Storage Temperature :
-20°C
Reference :
Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)
Anderson, M.W., et al. Am. J. Clin. Pathol. 133(3):473-483(2010)
Amundsen, S.S., et al. Genes Immun. 11(1):79-86(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/47/033428_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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