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product summary
company name :
US Biological
product type :
antibody
product name :
CCNH, CT (CCNH, Cyclin-H, MO15-associated protein, p34, p37) (APC)
catalog :
033413-APC
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
APC
reactivity :
human
product information
Catalog Number :
033413-APC
Product wo Prefix :
CCNH, CT (CCNH, Cyclin-H, MO15-associated protein, p34, p37) (APC)
Host :
rabbit
Product Type :
Pab
Conjugate :
APC
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with CDK7 kinase and ring finger protein MAT1. The kinase complex is able to phosphorylate CDK2 and CDC2 kinases, thus functions as a CDK-activating kinase (CAK). This cyclin and its kinase partner are components of TFIIH, as well as RNA polymerase II protein complexes. They participate in two different transcriptional regulation processes, suggesting an important link between basal transcription control and the cell cycle machinery. A pseudogene of this gene is found on chromosome 4. Alternate splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, Flow Cytometry, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Flow Cytometry: 1:10-50 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
Alternate Name :
CCNH, Cyclin-H, MO15-associated protein, p34, p37
Immunogen :
CCNH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-299 amino acids from the C-terminal region of human CCNH.
Specificity :
Human
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Concentration :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: CCNH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 267-299 amino acids from the C-terminal region of human CCNH. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FC FL WB
Storage Temperature :
4°C Do Not Freeze
Reference :
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010) Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009) Young, R.P., et al. Postgrad Med J 85(1008):515-524(2009) Kweekel, D.M., et al. Br. J. Cancer 101(2):357-362(2009) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/37/033413-APC_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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