antibody

CCL21, ID (CCL21, SCYA21, C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21) (APC)

033364-APC

200 ul

polyclonal

domestic rabbit

APC

CCL21, ID (CCL21, SCYA21, C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21) (APC)

rabbit

Pab

APC

Antibodies

200 ul

IgG

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu Mo

CCL21, SCYA21, C-C motif chemokine 21, 6Ckine, Beta-chemokine exodus-2, Secondary lymphoid-tissue chemokine, Small-inducible cytokine A21

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 23-52 in the central region of human CCL21, NP_002980.1; O00585.

Recognizes human CCL21. Species Crossreactivity: mouse

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 23-52 in the central region of human CCL21, NP_002980.1; O00585. Specificity: Recognizes human CCL21. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

FL IHC WB

4°C Do Not Freeze

1. Rey-Gallardo, A., et al. Glycobiology 20(9):1139-1146(2010) 2. Cuesta-Mateos, C., et al. Exp. Hematol. 38(9):756-764(2010) 3. Sundqvist, J., et al. Fertil. Steril. (2010) In press 4. Plant, D., et al. Ann. Rheum. Dis. 69(8):1548-1553(2010) 5. Farragher, T.M., et al. Arthritis Care Res (Hoboken) 62(5):676-682(2010)

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