Bax, ID (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)

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product summary

company name :

US Biological

product type :

antibody

product name :

Bax, ID (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)

catalog :

032434

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

032434

Product wo Prefix :

Bax, ID (BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

BAX, BCL2L4, Apoptosis regulator BAX, Bcl-2-like protein 4

Immunogen :

Bax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the Central region of human Bax.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: Bax antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-98 amino acids from the Central region of human Bax. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Montessuit, S., et al. Cell 142(6):889-901(2010) Ding, J., et al. J. Biol. Chem. 285(37):28749-28763(2010) Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press : Yu, D.K., et al. Zhonghua Zhong Liu Za Zhi 32(5):324-327(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/25/032434_1.jpg