antibody

ATP6V1A, ID (ATP6V1A, ATP6A1, ATP6V1A1, VPP2, V-type proton ATPase catalytic subunit A, V-ATPase 69kD subunit, Vacuolar ATPase isoform VA68, Vacuolar proton pump subunit alpha) (AP)

032296-AP

200 ul

polyclonal

domestic rabbit

AP

ATP6V1A, ID (ATP6V1A, ATP6A1, ATP6V1A1, VPP2, V-type proton ATPase catalytic subunit A, V-ATPase 69kD subunit, Vacuolar ATPase isoform VA68, Vacuolar proton pump subunit alpha) (AP)

rabbit

Pab

AP

Antibodies

200 ul

IgG

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Applications: Suitable for use in Western Blot, Immunohistochemistry Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

ATP6V1A, ATP6A1, ATP6V1A1, VPP2, V-type proton ATPase catalytic subunit A, V-ATPase 69kD subunit, Vacuolar ATPase isoform VA68, Vacuolar proton pump subunit alpha

ATP6V1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 447~477 amino acids from the Central region of human ATP6V1A.

Human

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: ATP6V1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 447~477 amino acids from the Central region of human ATP6V1A. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E IHC WB

4°C Do Not Freeze

Martins-de-Souza, D., et al. J Psychiatr Res 43(11):978-986(2009) Martins-de-Souza, D., et al. BMC Psychiatry 9, 17 (2009) Lu, M., et al. J. Biol. Chem. 282(34):24495-24503(2007) Ahmed, M., et al. J. Proteome Res. 4(3):931-940(2005) Morel, N. Biol. Cell 95(7):453-457(2003)

https://usbio-images.r.worldssl.net/prodimages/14/032296-AP_1.jpg