ATF4, phosphorylated (pS245) (Tax-responsive enhancer element B67, ATF4 protein)

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product summary

company name :

US Biological

product type :

antibody

product name :

ATF4, phosphorylated (pS245) (Tax-responsive enhancer element B67, ATF4 protein)

catalog :

032162

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

032162

Product wo Prefix :

ATF4, phosphorylated (pS245) (Tax-responsive enhancer element B67, ATF4 protein)

Host :

rabbit

Product Type :

Pab

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication. Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA1:1,000 Dot blot 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

Tax-responsive enhancer element B67, ATF4 protein

Immunogen :

Phospho-ATF4-pS245 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S245 of human ATF4.

Specificity :

Human

Purity :

Purified by peptide immunoaffinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by peptide immunoaffinity chromatography. Immunogen: Phospho-ATF4-pS245 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S245 of human ATF4. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB E

Storage Temperature :

-20°C

Reference :

Gombart,A.F., J. Leukoc. Biol. 81 (6), 1535-1547 (2007) Jousse,C., J. Biol. Chem. 282 (21), 15851-15861 (2007) Kakiuchi,C., Neurosci. Lett. 417 (3), 316-321 (2007) Marchand,A., J. Biol. Chem. 281 (28), 19124-19133 (2006)