ATF3, CT (ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ATF3, CT (ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3)

catalog :

032160

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

032160

Product wo Prefix :

ATF3, CT (ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. Applications: Suitable for use in Western Blot, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

ATF3, Cyclic AMP-dependent transcription factor ATF-3, Activating transcription factor 3

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 140-168 in the C-terminal region of human ATF3. Species sequence homology: bovine, mouse, rat

Specificity :

Recognizes human ATF3.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 140-168 in the C-terminal region of human ATF3. Species sequence homology: bovine, mouse, rat Specificity: Recognizes human ATF3. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 2. Lee, S.H., et al. Oncogene 29(37):5182-5192(2010) 3. Park, H.J., et al. Biochem. Biophys. Res. Commun. 400(1):72-77(2010) 4. Wu, X., et al. Nature 465(7296):368-372(2010) 5. Koh, I.U., et al. FEBS J. 277(10):2304-2317(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/4/032160_1.png