ASGR1, NT (ASGR1, CLEC4H1, Asialoglycoprotein receptor 1, C-type lectin domain family 4 member H1, Hepatic lectin H1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ASGR1, NT (ASGR1, CLEC4H1, Asialoglycoprotein receptor 1, C-type lectin domain family 4 member H1, Hepatic lectin H1)

catalog :

032134

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

032134

Product wo Prefix :

ASGR1, NT (ASGR1, CLEC4H1, Asialoglycoprotein receptor 1, C-type lectin domain family 4 member H1, Hepatic lectin H1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Partially deglycosylated plasma glycoproteins and immunoglobulin IgA2 allotypes are efficiently and specifically removed from circulation by a receptor-mediated process. The asialoglycoprotein receptor binds to desialylated (galactosyl-terminal) glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociate. Then the receptor is recycled back to the cell surface and the ligand is transported to the lysosomes for degradation. Alternatively spliced transcript variants encoding distinct isoforms have been identified. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

ASGR1, CLEC4H1, Asialoglycoprotein receptor 1, C-type lectin domain family 4 member H1, Hepatic lectin H1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human ASGR1. Swiss/UniProt Accession: P07306.

Specificity :

Recognizes human ASGR1.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1-30 in the N-terminal region of human ASGR1. Swiss/UniProt Accession: P07306. Specificity: Recognizes human ASGR1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Yang, J., et al. Arch. Virol. 155(6):881-888 (2010). 2. Liu, J., et al. PLoS ONE 5 (9), E12934 (2010). 3. Sorensen, A.L., et al. Blood 114(8):1645-1654 (2009). 4. Oh, J.H., et al. Mamm. Genome 16(12):942-954 (2005). 5. Yik, J.H., et al. J. Biol. Chem. 277(43):40844-40852 (2002)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/13/032134_1.pdf