ALDOB, NT (ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolase) (AP) | US Biological 031782-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

ALDOB, NT (ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolase) (AP)

catalog :

031782-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

031782-AP

Product wo Prefix :

ALDOB, NT (ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolase) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5% of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

ALDOB, ALDB, Fructose-bisphosphate aldolase B, Liver-type aldolase

Immunogen :

ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic between 30-60 amino acids selected from the N-terminal region of human ALDOB.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: ALDOB antibody is generated from rabbits immunized with a KLH conjugated synthetic between 30-60 amino acids selected from the N-terminal region of human ALDOB. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Bouteldja, N., et al. J. Inherit. Metab. Dis. 33(2):105-112(2010) Coffee, E.M., et al. J. Inherit. Metab. Dis. 33(1):33-42(2010) Segat, L., et al. J. Gastroenterol. Hepatol. 24(12):1840-1846(2009) Davit-Spraul, A., et al. Mol. Genet. Metab. 94(4):443-447(2008) Eriksson, A., et al. BMC Gastroenterol 8, 34 (2008) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/2/031782-AP_1.jpg