TP63 (TP63, KET, P63, P73H, P73L, TP73L, Tumor protein 63, Chronic ulcerative stomatitis protein, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p40, p51)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TP63 (TP63, KET, P63, P73H, P73L, TP73L, Tumor protein 63, Chronic ulcerative stomatitis protein, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p40, p51)

catalog :

031304

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

603CT12.4.3

reactivity :

human

product information

Catalog Number :

031304

Product wo Prefix :

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

603CT12.4.3

Isotype :

IgM

Desc1 :

This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:200-1:1600 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

TP63, KET, P63, P73H, P73L, TP73L, Tumor protein 63, Chronic ulcerative stomatitis protein, Keratinocyte transcription factor KET, Transformation-related protein 63, Tumor protein p73-like, p40, p51

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 651-680 from human TP63.

Specificity :

Recognizes human TP63.

Purity :

Ascites

Form :

Supplied as a liquid, 0.09% sodium azide

Concentration :

Not Determined

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 603CT12.4.3 Host: mouse Source: human Concentration: Not Determined Form: Supplied as a liquid, 0.09% sodium azide Purity: Ascites Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 651-680 from human TP63. Specificity: Recognizes human TP63. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Du, Z., et al. Cancer Sci. 101(11):2417-2424(2010). 2. Lena, A.M., et al. Biochem. Biophys. Res. Commun. 401(4):568-573(2010). 3. Miki, D., et al. Nat. Genet. 42(10):893-896(2010). 4. Yang, A., et al. PLoS ONE 5 (7), E11572 (2010). 5. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/3/031304_1.pdf