TNINI3 (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TNINI3 (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

catalog :

031300

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

358CT10.3.6

reactivity :

human

product information

Catalog Number :

031300

Product wo Prefix :

TNINI3 (TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

358CT10.3.6

Isotype :

IgM

Desc1 :

Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:500 - 1:8000 Optimal dilution to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

TNNI3, TNNC1, Troponin I, cardiac muscle, Cardiac troponin I

Immunogen :

KLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa 52-79 of human TNINI3. Swiss/Uniprot Accession: P19429. Species Sequence Homology: bovine, equine and rabbit

Specificity :

Recognizes human TNINI3.

Purity :

Ascites

Form :

Supplied as a liquid, 0.09% sodium azide.

Concentration :

Not Determined

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 358CT10.3.6 Host: mouse Source: human Concentration: Not Determined Form: Supplied as a liquid, 0.09% sodium azide. Purity: Ascites Immunogen: KLH-conjugated synthetic peptide corresponding to a portion of amino acids within aa 52-79 of human TNINI3. Swiss/Uniprot Accession: P19429. Species Sequence Homology: bovine, equine and rabbit Specificity: Recognizes human TNINI3. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Millat, G., et al. Clin. Chim. Acta 411 (23-24), 1983-1991 (2010). 2. Murakami, C., et al. Leg Med (Tokyo) 12(6):280-283(2010). 3. Millat, G., et al. Eur J Med Genet 53(5):261-267(2010). 4. Di Chiara, A., et al. J Cardiovasc Med (Hagerstown) 11(8):587-592(2010). 5. Napan, S., et al. Coron. Artery Dis. 21(5):261-265(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/29/031300_1.png