TLR3 (TLR3, Toll-like receptor 3, CD_antigen=CD283) | US Biological 031297 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TLR3 (TLR3, Toll-like receptor 3, CD_antigen=CD283)

catalog :

031297

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

303CT19.9.2

The same clone is also sold as:

MyBioSource: MBS9200129

reactivity :

human

product information

Catalog Number :

031297

Product wo Prefix :

TLR3 (TLR3, Toll-like receptor 3, CD_antigen=CD283)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

303CT19.9.2

Isotype :

IgM,k

Desc1 :

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

TLR3, Toll-like receptor 3, CD_antigen=CD283, Flags: Precursor

Immunogen :

TLR3 Mab is generated from mouse immunized with TLR3 recombinant protein.

Specificity :

Mouse

Purity :

Purified by ammonium sulfate precipitation.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM,k Clone No: 303CT19.9.2 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by ammonium sulfate precipitation. Immunogen: TLR3 Mab is generated from mouse immunized with TLR3 recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) Perez de Diego, R., et al. Immunity 33(3):400-411(2010) Zhou, Y., et al. Immunology 131(1):40-49(2010) Perrot, I., et al. J. Immunol. 185(4):2080-2088(2010) Paone, A., et al. Neoplasia 12(7):539-549(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/12/031297_1.jpg