TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, Polyergin)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, Polyergin)

catalog :

031282

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

220ct16.4.3.1

The same clone is also sold as:

Abnova: MAB12310
Invitrogen: MA5-37505

reactivity :

human

product information

Catalog Number :

031282

Product wo Prefix :

TGFB2 (TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, Polyergin)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

220ct16.4.3.1

Isotype :

IgG1,k

Desc1 :

This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:500~16000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

TGFB2, Transforming growth factor beta-2, BSC-1 cell growth inhibitor, Cetermin, Glioblastoma-derived T-cell suppressor factor, Polyergin

Immunogen :

TGFB2 Mab is generated from mouse immunized with TGFB2 recombinant protein.

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: 220ct16.4.3.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: TGFB2 Mab is generated from mouse immunized with TGFB2 recombinant protein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Nalpas, B., et al. Gut 59(8):1120-1126(2010) Bailey, S.D., et al. Diabetes Care (2010) In press Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010) Sambo, M.R., et al. PLoS ONE 5 (6), E11141 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/031282_1.jpg