This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
SNAI (SNAI1, SNAH, Zinc finger protein SNAI1, Protein snail homolog 1)
catalog :
031251
quantity :
100 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
reactivity :
human
product information
Catalog Number :
031251
Product wo Prefix :
SNAI (SNAI1, SNAH, Zinc finger protein SNAI1, Protein snail homolog 1)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
100 ul
Clone # USB :
118CT12.3.2
Isotype :
IgM,k
Desc1 :
The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2.
Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.
Recommended Dilutions:
Western Blot: 1:100-1:200
Immunohistochemistry (FFPE): 1:10-1:50
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
SNAI1, SNAH, Zinc finger protein SNAI1, Protein snail homolog 1
Immunogen :
Recombinant protein corresponding to SNAI (O95863)
Specificity :
Recognizes human SNAI.
Purity :
Ascites
Form :
Supplied as a liquid, 0.09% sodium azide
Concentration :
Not Determined
Desc2 :
Product Type: Mab
Isotype: IgM,k
Clone No: 118CT12.3.2
Host: mouse
Source: human
Concentration: Not Determined
Form: Supplied as a liquid, 0.09% sodium azide
Purity: Ascites
Immunogen: Recombinant protein corresponding to SNAI (O95863)
Specificity: Recognizes human SNAI.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
-20°C
Reference :
1. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. 2. Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility hot-spot. Johnatty SE, et al. PLoS Genet, 2010 Jul 8. PMID 20628624. 3. miR-661 expression in SNAI1-induced epithelial to mesenchymal transition contributes to breast cancer cell invasion by targeting Nectin-1 and StarD10 messengers. Vetter G, et al. Oncogene, 2010 Aug 5. PMID 20543867. 4. Snail transcription factor regulates neuroendocrine differentiation in LNCaP prostate cancer cells. McKeithen D, et al. Prostate, 2010 Jun 15. PMID 20166136. 5. Tumor expression of integrin-linked kinase (ILK) correlates with the expression of the E-cadherin repressor snail: an immunohistochemical study in ductal pancreatic adenocarcinoma. Schaeffer DF, et al. Virchows Arch, 2010 Mar. PMID 20091050.
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/6/031251_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
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