S100B (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B)

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product summary

company name :

US Biological

product type :

antibody

product name :

S100B (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B)

catalog :

031235

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

271CT14.3.3

reactivity :

human

product information

Catalog Number :

031235

Product wo Prefix :

S100B (S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

271CT14.3.3

Isotype :

IgM,k

Desc1 :

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

S100B, Protein S100-B, S-100 protein beta chain, S-100 protein subunit beta, S100 calcium-binding protein B

Immunogen :

S100B Mab is generated from mouse immunized with S100B recombinant protein.

Specificity :

Mouse

Purity :

Purified by ammonium sulfate precipitation.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM,k Clone No: 271CT14.3.3 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by ammonium sulfate precipitation. Immunogen: S100B Mab is generated from mouse immunized with S100B recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Sahoo, N., et al. FEBS Lett. 584(18):3896-3900(2010) Lin, J., et al. J. Biol. Chem. 285(35):27487-27498(2010) van Dieck, J., et al. FEBS Lett. 584(15):3269-3274(2010) Egberts, F., et al. Anticancer Res. 30(5):1799-1805(2010) Boutsikou, T., et al. Mediators Inflamm. 2010, 790605 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/20/031235_1.jpg