PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase) (Biotin) | US Biological 031207-Biotin product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase) (Biotin)

catalog :

031207-Biotin

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

206CT5.4.2

The same clone is also sold as:

Invitrogen: MA5-37501

reactivity :

human

product information

Catalog Number :

031207-Biotin

Product wo Prefix :

PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase) (Biotin)

Host :

mouse

Product Type :

Mab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

206CT5.4.2

Isotype :

IgG2a,K

Desc1 :

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100~500 Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase

Immunogen :

PRKAA2 Mab is generated from mouse immunized with PRKAA2 recombinant protein.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG2a,K Clone No: 206CT5.4.2 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: PRKAA2 Mab is generated from mouse immunized with PRKAA2 recombinant protein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jassim, G., et al. Pharmacopsychiatry (2010) In press Bungard, D., et al. Science 329(5996):1201-1205(2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/31/031207-Biotin_1.jpg