PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase)

catalog :

031206

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

206CT5.4.2

The same clone is also sold as:

Invitrogen: MA5-37501

reactivity :

human

product information

Catalog Number :

031206

Product wo Prefix :

PRKAA2 (PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

206CT5.4.2

Isotype :

IgG2a,k

Desc1 :

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:500~2000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

PRKAA2, AMPK, AMPK2, 5'-AMP-activated protein kinase catalytic subunit alpha-2, Acetyl-CoA carboxylase kinase, Hydroxymethylglutaryl-CoA reductase kinase

Immunogen :

PRKAA2 Mab is generated from mouse immunized with PRKAA2 recombinant protein.

Specificity :

Mouse

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG2a,k Clone No: 206CT5.4.2 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: PRKAA2 Mab is generated from mouse immunized with PRKAA2 recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Jablonski, K.A., et al. Diabetes 59(10):2672-2681(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jassim, G., et al. Pharmacopsychiatry (2010) In press Bungard, D., et al. Science 329(5996):1201-1205(2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/11/031206_1.jpg