PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,)

catalog :

031183

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

275CT1

reactivity :

human

product information

Catalog Number :

031183

Product wo Prefix :

PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

275CT1

Isotype :

IgG1,k

Desc1 :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:8~30 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

Beta-type platelet-derived growth factor receptor,PDGFRB,

Immunogen :

PDGFRB Mab is generated from mouse immunized with PDGFRB recombinant protein.

Specificity :

Mouse

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: 275CT1 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: PDGFRB Mab is generated from mouse immunized with PDGFRB recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Getachew, R., et al. Endocrinology 151(9):4356-4367(2010) Roder, C., et al. Acta Neurochir (Wien) (2010) In press Shim, A.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(25):11307-11312(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)