PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,) (Biotin) | US Biological 031183-Biotin product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,) (Biotin)

catalog :

031183-Biotin

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

275CT1

reactivity :

human

product information

Catalog Number :

031183-Biotin

Product wo Prefix :

PDGFR (Beta-type platelet-derived growth factor receptor,PDGFRB,) (Biotin)

Host :

mouse

Product Type :

Mab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

275CT1

Isotype :

IgG1,k

Desc1 :

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:8~30 Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

Beta-type platelet-derived growth factor receptor,PDGFRB,

Immunogen :

PDGFRB Mab is generated from mouse immunized with PDGFRB recombinant protein.

Specificity :

Mouse

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: 275CT1 Host: mouse Source: mouse Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: PDGFRB Mab is generated from mouse immunized with PDGFRB recombinant protein. Specificity: Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Getachew, R., et al. Endocrinology 151(9):4356-4367(2010) Roder, C., et al. Acta Neurochir (Wien) (2010) In press Shim, A.H., et al. Proc. Natl. Acad. Sci. U.S.A. 107(25):11307-11312(2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)