Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL) (APC) | US Biological 031162-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL) (APC)

catalog :

031162-APC

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

487CT6.9.2

The same clone is also sold as:

Invitrogen: MA5-37575

reactivity :

human

product information

Catalog Number :

031162-APC

Product wo Prefix :

Notch3, CT (Notch homolog 3, Drosophila, hN3, CASIL, CADASIL) (APC)

Host :

mouse

Product Type :

Mab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

487CT6.9.2

Isotype :

IgG1

Desc1 :

This gene encodes the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). [provided by RefSeq]. Applications: Suitable for use in Western Blot, FLISA. Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze APC conjugates. Light sensitive. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Immunogen :

NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 487CT6.9.2 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein G affinity chromatography. Immunogen: NOTCH3 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from the C-term region of human NOTCH3. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Liu, H., et al. Circ. Res. 107(7):860-870(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Menon, S., et al. Cephalalgia (2010) In press Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) Johnatty, S.E., et al. PLoS Genet. 6 (7), E1001016 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/38/031162-APC_1.jpg