NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog) (Biotin) | US Biological 031151-Biotin product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog) (Biotin)

catalog :

031151-Biotin

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

60CT77.1.1

The same clone is also sold as:

Aviva Systems Biology: OAAB06653
Abnova: MAB12279

reactivity :

human

product information

Catalog Number :

031151-Biotin

Product wo Prefix :

NANOG (NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog) (Biotin)

Host :

mouse

Product Type :

Mab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

60CT77.1.1

Isotype :

IgG1,k

Desc1 :

Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes (By similarity). Acts as a transcriptional activator or repressor (By similarity). Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' (By similarity). When overexpressed, promotes cells to enter into S phase and proliferation (By similarity). Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:100~250 Immunohistochemistry: 1:10~50 Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

NANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog

Immunogen :

NANOG Mab is generated from mouse immunized with NANOG recombinant protein.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1,k Clone No: 60CT77.1.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: NANOG Mab is generated from mouse immunized with NANOG recombinant protein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

Trubiani, O., et al. J. Cell. Physiol. 225(1):123-131(2010) Po, A., et al. EMBO J. 29(15):2646-2658(2010) Zbinden, M., et al. EMBO J. 29(15):2659-2674(2010) Moretto-Zita, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(30):13312-13317(2010) Kuijk, E.W., et al. PLoS ONE 5 (6), E10987 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/031151-Biotin_1.jpg