This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
MVP, NT (MVP, LRP, Major vault protein, Lung resistance-related protein)
catalog :
031140
quantity :
100 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
599CT2.4.1
reactivity :
human
product information
Catalog Number :
031140
Product wo Prefix :
MVP, NT (MVP, LRP, Major vault protein, Lung resistance-related protein)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
100 ul
Clone # USB :
599CT2.4.1
Isotype :
IgG1
Desc1 :
This gene encodes the major vault protein which is a lung resistance-related protein. Vaults are multi-subunit structures that may be involved in nucleo-cytoplasmic transport. This protein mediates drug resistance, perhaps via a transport process. It is widely distributed in normal tissues, and overexpressed in multidrug-resistant cancer cells. The protein overexpression is a potentially useful marker of clinical drug resistance. This gene produces two transcripts by using two alternative exon 2 sequences; however, the open reading frames are the same in both transcripts.
Applications:
Suitable for use in Western Blot, ELISA.
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100~1600
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Calc Crossreactivity :
Hu
Alternate Name :
MVP, LRP, Major vault protein, Lung resistance-related protein
Immunogen :
MVP Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human MVP.
Specificity :
Human
Purity :
Ascites
Form :
Supplied as a liquid, crude ascites with 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Mab
Isotype: IgG1
Clone No: 599CT2.4.1
Host: mouse
Source: human
Concentration: As reported
Form: Supplied as a liquid, crude ascites with 0.09% sodium azide.
Purity: Ascites
Immunogen: MVP Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human MVP.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E WB
Storage Temperature :
-20°C
Reference :
Li, J., et al. Lung Cancer 69(1):116-122(2010)
Liang, P., et al. Biochem. Cell Biol. 88(3):445-450(2010)
An, H.J., et al. Cell Biochem. Funct. 27(5):289-295(2009)
Li, L., et al. Zhonghua Zhong Liu Za Zhi 31(3):199-202(2009)
Lara, P.C., et al. Radiat Oncol 4, 29 (2009)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/41/031140_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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