MMP14, CT (MMP14, Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase) (APC) discontinued | US Biological 031127-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MMP14, CT (MMP14, Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase) (APC) discontinued

catalog :

031127-APC

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

133CT15.10.5.1

The same clone is also sold as:

Abnova: MAB12762
Invitrogen: MA5-37473

reactivity :

human

product information

Catalog Number :

031127-APC

Product wo Prefix :

MMP14, CT (MMP14, Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase) (APC) discontinued

Host :

mouse

Product Type :

Mab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

133CT15.10.5.1

Isotype :

IgM

Desc1 :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion. Applications: Suitable for use in Western Blot, Immunofluorescence, FLISA. Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100~500 Immunofluorescence: 1:10~50 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze APC conjugates. Light sensitive. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

MMP14, Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase

Immunogen :

MMP14 Mab is generated from mouse immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP14.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 133CT15.10.5.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein G affinity chromatography. Immunogen: MMP14 Mab is generated from mouse immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MMP14. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL IF WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Onimaru, M., et al. Arterioscler. Thromb. Vasc. Biol. 30(4):818-826(2010) Wipff, J., et al. J. Rheumatol. 37(3):599-602(2010) Liao, M.C., et al. Biochemistry 49(6):1127-1136(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/48/031127-APC_1.jpg