MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

catalog :

031124

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

628CT4.6.1

The same clone is also sold as:

Invitrogen: MA5-37606

reactivity :

human

product information

Catalog Number :

031124

Product wo Prefix :

MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

628CT4.6.1

Isotype :

IgG1

Desc1 :

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~400 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

Immunogen :

MLH1 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human MLH1.

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 628CT4.6.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: MLH1 Mab is generated from mice immunized with a KLH conjugated synthetic peptide selected from human MLH1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Ling, Z.Q., et al. Cancer Lett. 297(2):244-251(2010) Qi, Y., et al. J. Biol. Chem. 285(43):33010-33017(2010) Borras, E., et al. Cancer Res. 70(19):7379-7391(2010) Mangoni, M., et al. Int. J. Radiat. Oncol. Biol. Phys. (2010) In press Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/5/031124_1.jpg