MBP (MBP, Myelin basic protein, Myelin A1 protein, Myelin membrane encephalitogenic protein)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MBP (MBP, Myelin basic protein, Myelin A1 protein, Myelin membrane encephalitogenic protein)

catalog :

031114

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

408CT17.4.3

reactivity :

human

product information

Catalog Number :

031114

Product wo Prefix :

MBP (MBP, Myelin basic protein, Myelin A1 protein, Myelin membrane encephalitogenic protein)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

408CT17.4.3

Isotype :

IgM

Desc1 :

The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunofluorescence, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:5000~16000 Immunofluorescence: 1:10~50 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

MBP, Myelin basic protein, Myelin A1 protein, Myelin membrane encephalitogenic protein

Immunogen :

Purified His-tagged MBP protein (fragment).

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 408CT17.4.3 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: Purified His-tagged MBP protein (fragment). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF WB

Storage Temperature :

-20°C

Reference :

Walsh, C.M., et al. Biochem. J. 430(3):453-460(2010) Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Martins-de-Souza, D., et al. J Psychiatr Res (2010) In press Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Pan, H., et al. Sichuan Da Xue Xue Bao Yi Xue Ban 40(5):775-779(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/0/031114_1.jpg