KLF4 (Kruppel-like Factor 4, Epithelial Zinc Finger Protein, EZF, Gut-enriched Krueppel-like Factor, GKLF) (AP) | US Biological 031072-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

KLF4 (Kruppel-like Factor 4, Epithelial Zinc Finger Protein, EZF, Gut-enriched Krueppel-like Factor, GKLF) (AP)

catalog :

031072-AP

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

56CT5.1.6

The same clone is also sold as:

OriGene: AM11052PU-N

reactivity :

human

product information

Catalog Number :

031072-AP

Product wo Prefix :

KLF4 (Kruppel-like Factor 4, Epithelial Zinc Finger Protein, EZF, Gut-enriched Krueppel-like Factor, GKLF) (AP)

Host :

mouse

Product Type :

Mab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

56CT5.1.6

Isotype :

IgG2b,k

Desc1 :

KLF4, which is also known as the gut-enriched Kruppel-like factor (GKLF), is a zinc finger-containing transcription factor that belongs to the Kruppel-like family of transcription factors. KLF4 plays important roles during the proliferation and differentiation of epithelial cells. Especially, it is found predominantly in gut and has been shown to be expressed during growth arrest. KLF4 is also involved in cell cycle control since expression of KLF4 inhibits DNA synthesis by blocking the G1/S phase of the cell cycle. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Immunogen :

Recombinant protein corresponding to human KLF4.

Specificity :

Recognizes human KLF4. Species crossreactivity: mouse

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG2b,k Clone No: 56CT5.1.6 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: Recombinant protein corresponding to human KLF4. Specificity: Recognizes human KLF4. Species crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1.MCC-555-induced NAG-1 expression is mediated in part by KLF4. Cekanova M, et al. Eur J Pharmacol, 2010 Jul 10. PMID 20385121. Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression. Yori JL, et al. J Biol Chem, 2010 May 28. PMID 20356845. MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. Tian Y, et al. J Biol Chem, 2010 Mar 12. PMID 20075075. Genetic and epigenetic inactivation of Kruppel-like factor 4 in medulloblastoma. Nakahara Y, et al. Neoplasia, 2010 Jan. PMID 20072650. Kruppel-like factor 4 (Klf4) prevents embryonic stem (ES) cell differentiation by regulating Nanog gene expression. Zhang P, et al. J Biol Chem, 2010 Mar 19. PMID 20071344.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/19/031072-AP_1.png