ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (Biotin) | US Biological 030951-Biotin product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (Biotin)

catalog :

030951-Biotin

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

biotin

clone name :

415CT16.3.2.1

reactivity :

human

product information

Catalog Number :

030951-Biotin

Product wo Prefix :

ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (Biotin)

Host :

mouse

Product Type :

Mab

Conjugate :

Biotin

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

415CT16.3.2.1

Isotype :

IgG1

Desc1 :

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1

Immunogen :

Synthetic peptide corresponding to a portion within aa246-273 from human ESR1 protein, conjugated to KLH (NP_005294.1). Species sequence homology: bovine, mouse, porcine, rat

Specificity :

Recognized human ESR1 at ~31kD.

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 415CT16.3.2.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin. Purity: Purified by Protein G affinity chromatography. Immunogen: Synthetic peptide corresponding to a portion within aa246-273 from human ESR1 protein, conjugated to KLH (NP_005294.1). Species sequence homology: bovine, mouse, porcine, rat Specificity: Recognized human ESR1 at ~31kD. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

Storage Temperature :

-20°C

Reference :

1. Geradts, J., et al. Cancer Invest. 28(9):969-977(2010) 2. Hayes, D.F., et al. Clin. Pharmacol. Ther. 88(5):626-629(2010) 3. Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010) 4. Corbo, R.M., et al. J. Gerontol. A Biol. Sci. Med. Sci. (2010) In press 5. Kim, S., et al. Fertil. Steril. (2010) In press

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/45/030951-Biotin_1.jpg