ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (APC) | US Biological 030951-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (APC)

catalog :

030951-APC

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

APC

clone name :

415CT16.3.2.1

reactivity :

human

product information

Catalog Number :

030951-APC

Product wo Prefix :

ESR1/ER (ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1) (APC)

Host :

mouse

Product Type :

Mab

Conjugate :

APC

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

415CT16.3.2.1

Isotype :

IgG1

Desc1 :

This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters. Applications: Suitable for use in Western Blot, FLISA. Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze APC conjugates. Light sensitive. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

ESR1, ESR, NR3A1, Estrogen receptor, ER-alpha, Estradiol receptor, Nuclear receptor subfamily 3 group A member 1

Immunogen :

Purified His-tagged ESR1 protein (fragment).

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 415CT16.3.2.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein G affinity chromatography. Immunogen: Purified His-tagged ESR1 protein (fragment). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Geradts, J., et al. Cancer Invest. 28(9):969-977(2010) Hayes, D.F., et al. Clin. Pharmacol. Ther. 88(5):626-629(2010) Lupien, M., et al. Genes Dev. 24(19):2219-2227(2010) Corbo, R.M., et al. J. Gerontol. A Biol. Sci. Med. Sci. (2010) In press Kim, S., et al. Fertil. Steril. (2010) In press

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/6/030951-APC_1.jpg