CTNNB1 (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin) | US Biological 030896 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CTNNB1 (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

catalog :

030896

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

516CT4.3.3

reactivity :

human

product information

Catalog Number :

030896

Product wo Prefix :

CTNNB1 (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

516CT4.3.3

Isotype :

IgM

Desc1 :

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:200~1600 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

CTNNB1, CTNNB, Catenin beta-1, Beta-catenin

Immunogen :

Purified His-tagged CTNNB1 protein (fragment).

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 516CT4.3.3 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: Purified His-tagged CTNNB1 protein (fragment). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/030896_1.jpg