CSF1R (CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, Proto-oncogene c-Fms, CD_antigen=CD115)

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product summary

company name :

US Biological

product type :

antibody

product name :

CSF1R (CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, Proto-oncogene c-Fms, CD_antigen=CD115)

catalog :

030889

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

177CT7.1.1

reactivity :

human

product information

Catalog Number :

030889

Product wo Prefix :

CSF1R (CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, Proto-oncogene c-Fms, CD_antigen=CD115)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

177CT7.1.1

Isotype :

IgG

Desc1 :

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1000 Western Blot: 1:1000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

CSF1R, FMS, Macrophage colony-stimulating factor 1 receptor, CSF-1 receptor, Proto-oncogene c-Fms, CD_antigen=CD115, Flags: Precursor

Immunogen :

CSF1R Mab was raised using purified His-tagged recombinant human CSF1R.

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Clone No: 177CT7.1.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: CSF1R Mab was raised using purified His-tagged recombinant human CSF1R. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Shin, E.K., et al. Hum. Genet. 128(3):293-302(2010) Wei, S., et al. J. Leukoc. Biol. 88(3):495-505(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) Paniagua, R.T., et al. Arthritis Res. Ther. 12 (1), R32 (2010) Wooten, E.C., et al. PLoS ONE 5 (1), E8830 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/40/030889_1.jpg