COMT, NT (COMT, Catechol O-methyltransferase) | US Biological 030887 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

COMT, NT (COMT, Catechol O-methyltransferase)

catalog :

030887

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

630CT1.7.1

The same clone is also sold as:

Invitrogen: MA5-37612

reactivity :

human

product information

Catalog Number :

030887

Product wo Prefix :

COMT, NT (COMT, Catechol O-methyltransferase)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

630CT1.7.1

Isotype :

IgG1

Desc1 :

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~400 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

COMT, Catechol O-methyltransferase

Immunogen :

COMT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COMT.

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 630CT1.7.1 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: COMT antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 37-65 amino acids from the N-terminal region of human COMT. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Paloyelis, Y., et al. Neuropsychopharmacology 35(12):2414-2426(2010) Stroth, S., et al. Neurobiol Learn Mem 94(3):364-372(2010) Lim, J.H., et al. Pharmacogenet. Genomics 20(10):605-610(2010) Demetrovics, Z., et al. Compr Psychiatry 51(5):510-515(2010) Bodenmann, S., et al. Sleep 33(8):1027-1035(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/28/030887_1.jpg