CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD_antigen=CD40)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD_antigen=CD40)

catalog :

030851

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

647CT13.2.4

The same clone is also sold as:

MyBioSource: MBS9200224

reactivity :

human

product information

Catalog Number :

030851

Product wo Prefix :

CD40, CT (CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B Cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD_antigen=CD40)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

647CT13.2.4

Isotype :

IgG1

Desc1 :

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:100-1:1600 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CD40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, CDw40, CD_antigen=CD40, Flags: Precursor

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 247-276 in the C-terminal region of human CD40, UniProt Accession #P25942. Species sequence homology: mouse, porcine.

Specificity :

Recognizes human CD40.

Purity :

Ascites

Form :

Supplied as a liquid, 0.09% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 647CT13.2.4 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid, 0.09% sodium azide. Purity: Ascites Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 247-276 in the C-terminal region of human CD40, UniProt Accession #P25942. Species sequence homology: mouse, porcine. Specificity: Recognizes human CD40. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Rodriguez-Rodriguez, L., et al. J. Rheumatol. 37(10):2076-2080(2010) Lewis, J.P., et al. Genomics 96(4):211-219(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Blanco-Kelly, F., et al. PLoS ONE 5 (7), E11520 (2010) Soliman, M.A., et al. Egypt J Immunol 16(1):61-70(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/27/030851_1.jpg