This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
BMI1 (BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51) (APC)
catalog :
030810-APC
quantity :
200 ul
clonality :
monoclonal
host :
mouse
conjugate :
APC
clone name :
reactivity :
human
product information
Catalog Number :
030810-APC
Product wo Prefix :
BMI1 (BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51) (APC)
Host :
mouse
Product Type :
Mab
Conjugate :
APC
Category :
Antibodies
Size1 :
200 ul
Clone # USB :
282CT3.7.6
Isotype :
IgG1,k
Desc1 :
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Applications:
Suitable for use in Western Blot, Immunofluorescence and FLISA. Other applications have not been tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
Alternate Name :
BMI1, PCGF4, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51
Immunogen :
Recombinant protein corresponding to human BMI1.
Specificity :
Recognizes human BMI1.
Purity :
Purified by Protein G affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Concentration :
As reported
Desc2 :
Product Type: Mab
Isotype: IgG1,k
Clone No: 282CT3.7.6
Host: mouse
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity: Purified by Protein G affinity chromatography.
Immunogen: Recombinant protein corresponding to human BMI1.
Specificity: Recognizes human BMI1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FL IF WB
Storage Temperature :
4°C Do Not Freeze
Reference :
1. Ismail, I.H., et al. J. Cell Biol. 191(1):45-60( 2010) 2. Yang, M.H., et al. Nat. Cell Biol. 12(10):982-992(2010) 3. Kikuchi, J., et al. Cancer 116(12):3015-3024(2010) 4. Honig, A., et al. Anticancer Res. 30(5):1559-1564(2010) 5. Venkataraman, S., et al. PLoS ONE 5 (6), E10748 (2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/26/030810-APC_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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