Androgen Receptor Protein (AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Androgen Receptor Protein (AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4)

catalog :

030771

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

549CT16.1.4

reactivity :

human

product information

Catalog Number :

030771

Product wo Prefix :

Androgen Receptor Protein (AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

549CT16.1.4

Isotype :

IgA

Desc1 :

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~250 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4

Immunogen :

Purified His-tagged Androgen Receptor Protein (fragment).

Specificity :

Human

Purity :

Purified by ammonium sulfate precipitation.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgA Clone No: 549CT16.1.4 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide. Purity: Purified by ammonium sulfate precipitation. Immunogen: Purified His-tagged Androgen Receptor Protein (fragment). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Shu, S.K., et al. J. Biol. Chem. 285(43):33045-33053(2010) Nedelsky, N.B., et al. Neuron 67(6):936-952(2010) Panda, B., et al. Gynecol. Endocrinol. (2010) In press Schneider, G., et al. Am J Geriatr Psychiatry (2010) In press Guadalupe-Grau, A., et al. PLoS ONE 5 (7), E11529 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/33/030771_1.jpg