AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II) (AP) | US Biological 030750-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II) (AP)

catalog :

030750-AP

quantity :

200 ul

clonality :

monoclonal

host :

mouse

conjugate :

clone name :

656CT5.8.4

reactivity :

human

product information

Catalog Number :

030750-AP

Product wo Prefix :

AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II) (AP)

Host :

mouse

Product Type :

Mab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Clone # USB :

656CT5.8.4

Isotype :

IgG1

Desc1 :

The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~1000 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C with the addition of glycerol. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Do not freeze alkaline phosphatase conjugates which could result in a substantial loss of enzymatic activity. Light sensitive. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

AGT, SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II

Immunogen :

AGT Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human AGT.

Specificity :

Recognizes human AGT.

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 656CT5.8.4 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: AGT Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human AGT. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Desong, Liu., et al. J Renin Angiotensin Aldosterone Syst 11(4):248-255(2010) Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) Hajjar, I., et al. J Am Geriatr Soc 58(6):1035-1042(2010) Kiec-Wilk, B., et al. Prz. Lek. 67(3):151-156(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/22/030750-AP_1.jpg