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product summary
company name :
US Biological
product type :
antibody
product name :
AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II)
catalog :
030749
quantity :
100 ul
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
656CT5.8.4
reactivity :
human
product information
Catalog Number :
030749
Product wo Prefix :
AGT, NT (SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II)
Host :
mouse
Product Type :
Mab
Category :
Antibodies
Size1 :
100 ul
Clone # USB :
656CT5.8.4
Isotype :
IgG1
Desc1 :
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:200~800 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Calc Crossreactivity :
Hu
Alternate Name :
AGT, SERPINA8, Angiotensinogen, Serpin A8, Angiotensin-1, Angiotensin I, Angiotensin-2, Angiotensin II, Angiotensin-3, Angiotensin III, Des-Asp[1]-angiotensin II
Immunogen :
AGT antibody is generated from mouses immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human AGT.
Specificity :
Human
Purity :
Ascites
Form :
Supplied as a liquid, crude ascites with 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Mab Isotype: IgG1 Clone No: 656CT5.8.4 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: AGT antibody is generated from mouses immunized with a KLH conjugated synthetic peptide between 36-65 amino acids from the N-terminal region of human AGT. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E WB
Storage Temperature :
-20°C
Reference :
Desong, Liu., et al. J Renin Angiotensin Aldosterone Syst 11(4):248-255(2010) Procopciuc, L.M., et al. Eur. J. Intern. Med. 21(5):414-418(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) Hajjar, I., et al. J Am Geriatr Soc 58(6):1035-1042(2010) Kiec-Wilk, B., et al. Prz. Lek. 67(3):151-156(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/16/030749_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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