Fetoprotein, Alpha (Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein precursor, FETA, HPAFP)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Fetoprotein, Alpha (Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein precursor, FETA, HPAFP)

catalog :

030747

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

143CT50.11.8

reactivity :

human

product information

Catalog Number :

030747

Product wo Prefix :

Fetoprotein, Alpha (Alpha-1-fetoprotein, Alpha-fetoglobulin, Alpha-fetoprotein precursor, FETA, HPAFP)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

143CT50.11.8

Isotype :

IgM

Desc1 :

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100~500 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Alternate Name :

AFP, HPAFP, Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin

Immunogen :

AFP Antibody antibody is generated from mouse immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human alpha 1 Fetoprotein.

Specificity :

Human

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgM Clone No: 143CT50.11.8 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: AFP Antibody antibody is generated from mouse immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human alpha 1 Fetoprotein. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Clinicopathologic features and prognostic factors in alpha-fetoprotein-producing gastric cancers: analysis of 104 cases. Liu X, et al. J Surg Oncol, 2010 Sep 1. PMID 20740583. Alpha-fetoprotein and tumour size are associated with microvascular invasion in explanted livers of patients undergoing transplantation with hepatocellular carcinoma. McHugh PP, et al. HPB (Oxford), 2010 Feb. PMID 20495646. Differential diagnosis of liver diseases using serum biomarkers. Cujic D, et al. J BUON, 2010 Jan-Mar. PMID 20414942. High-efficient expression, refolding and purification of functional recombinant C-terminal fragment of human alpha-fetoprotein. Sharapova OA, et al. Protein Expr Purif, 2010 Sep. PMID 20363333. Alpha-fetoprotein producing cells act as cancer progenitor cells in human cholangiocarcinoma. Ishii T, et al. Cancer Lett, 2010 Aug 1. PMID 20149523.

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/4/030747_1.jpg