ACHE, CT (Acetylcholinesterase) | US Biological 030736 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ACHE, CT (Acetylcholinesterase)

catalog :

030736

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

684CT8.3.4

The same clone is also sold as:

OriGene: TA328141

reactivity :

human

product information

Catalog Number :

030736

Product wo Prefix :

ACHE, CT (Acetylcholinesterase)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

684CT8.3.4

Isotype :

IgG1

Desc1 :

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. It is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. It is encoded by the single ACHE gene, and the structural diversity in the gene products arises from alternative mRNA splicing, and post-translational associations of catalytic and structural subunits. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits. The other, alternatively spliced form, expressed primarily in the erythroid tissues, differs at the C-terminal end, and contains a cleavable hydrophobic peptide with a GPI-anchor site. It associates with the membranes through the phosphoinositide (PI) moieties added post-translationally. Applications: Suitable for use in Western Blot, ELISA. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:200~3200 Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Calc Crossreactivity :

Hm Hu

Alternate Name :

ACHE, Acetylcholinesterase

Immunogen :

ACHE Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human ACHE.

Specificity :

Human, hamster

Purity :

Ascites

Form :

Supplied as a liquid, crude ascites with 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 684CT8.3.4 Host: mouse Source: human Concentration: As reported Form: Supplied as a liquid, crude ascites with 0.09% sodium azide. Purity: Ascites Immunogen: ACHE Mab is generated from mouses immunized with a KLH conjugated synthetic peptide selected from human ACHE. Specificity: Human, hamster Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Howard, T.D., et al. Environ. Health Perspect. 118(10):1395-1399(2010) Cadieux, C.L., et al. Chem. Biol. Interact. 187 (1-3), 229-233 (2010) Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Ohno, K., et al. Proc. Natl. Acad. Sci. U.S.A. 95(16):9654-9659(1998)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/43/030736_1.jpg