S100B | US Biological 030615 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

S100B

catalog :

030615

quantity :

100 ul

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B693

reactivity :

human

product information

Catalog Number :

030615

Product wo Prefix :

S100B

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ul

Clone # USB :

13B693

Isotype :

IgG1

Desc1 :

S100B (S100 calcium binding protein B) is a member of the S100 family of proteins containing 2 EF-hand calcium binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S-100 proteins and parvalbumin proteins are each expressed in neural tissues. In addition, S100B are present in a variety of other tissues, and calbindin is present in intestine and kidney. Parvalbumin B is found in many tumor tissues as well as in the organ of Corti. Calbindin, S-100 proteins and parvalbulmins have all been detected in leydig cells and the testis. These proteins are thought to play a role in hormone production and spermatogenesis. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. Applications: Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:10,000 Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

NEF; S100; S100beta

Immunogen :

Purified recombinant fragment of S100B expressed in E. coli.

Specificity :

Recognizes human S100B.

Purity :

Ascites

Form :

Supplied as a liquid in 0.03% sodium azide.

Concentration :

Not determined

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B693 Host: mouse Source: human Concentration: Not determined Form: Supplied as a liquid in 0.03% sodium azide. Purity: Ascites Immunogen: Purified recombinant fragment of S100B expressed in E. coli. Specificity: Recognizes human S100B. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Shapiro, L.A., et al., Brain Res. 1010(1-2): 17-21 (2004). 2. Sorci, G., et al., Mol. Cell Biol. 24(11): 4880-4894 (2004). 3. Zimmer, D.B., et al., Cell Mol. Biol. (Noisy-le-grand) 51(2): 201-214 (2005).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/23/030615_1.jpg