PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

catalog :

030572

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B650

reactivity :

human

product information

Catalog Number :

030572

Product wo Prefix :

PSAP (Cerebroside sulfate activator, FLJ00245, GLBA, MGC110993, Prosaposin, SAP1)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

13B650

Isotype :

IgG1

Desc1 :

This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:50-1:500 Flow Cytometry: 1:200-1:400 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. coli.

Specificity :

Human

Purity :

Purified

Form :

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B650 Host: mouse Source: human Concentration: As reported Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human PSAP (AA: 325-524 ) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IC IHC WB

Storage Temperature :

-20°C

Reference :

1.Biochem J. 2012 Jan 15;441(2):665-74. 2.Mol Cancer. 2010 Feb 4;9:30.