Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

catalog :

030512

quantity :

100 ug

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

13B590

reactivity :

human

product information

Catalog Number :

030512

Product wo Prefix :

Osteopontin (Bone Sialoprotein 1, SPP-1, Urinary Stone Protein, Uropontin, Nephropontin, Secreted Phosphoprotein 1, SPP1, BNSP, OPN, PSEC0156, ETA-1)

Host :

mouse

Product Type :

Mab

Category :

Antibodies

Size1 :

100 ug

Clone # USB :

13B590

Isotype :

IgG1

Desc1 :

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. Osteopontin, also named early T lymphocyte activation protein 1, secreted phosphoprotein, and bone sialoprotein 1, is a secreted acidic phosphorylated glycoprotein originally isolated from bone matrix. It has been shown to bind to different cell types through interactions with various integrins and CD44 variants. It has important functions in bone metabolism and inflammatory processes. Applications: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:200-1:1000 Immunocytochemistry: 1:200-1:1000 ELISA: 1:10000 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Immunogen :

Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli.

Specificity :

Human

Purity :

Purified

Form :

Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer

Concentration :

As reported

Desc2 :

Product Type: Mab Isotype: IgG1 Clone No: 13B590 Host: mouse Source: human Concentration: As reported Form: Purified antibody in PBS with 0.05% sodium azide and 0.5% protein stabilizer Purity: Purified Immunogen: Purified recombinant fragment of human SPP1 (AA: 167-314) expressed in E. coli. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IC IHC WB

Storage Temperature :

-20°C

Reference :

1.Blood. 2012 May 31;119(22):5215-20. 2.J Cancer Res Ther. 2011 Apr-Jun;7(2):138-42.